ALFAGEN, Your Long-Term Partner In Life-Science

Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological’s products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers’ one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offers pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.

Our Mission
To advance life science and improve human health through the provision of superior quality research reagents and CRO services.

Our People

• 900+ Research Staff & Growing
• 230+ staff with Master or PhD degree

Our Clients

Academic research institutions, biotech companies, and Pharmaceutical companies

Our Facility

• 279,800 sq ft Lab & Office Space
• 43,000 sq ft GMP Facility

Sino Biological's Core Business

Sino Biological is committed to providing high-quality recombinant protein and antibody reagents and to being a one-stop technical services shop for life science researchers around the world. All of our products are independently developed and produced. In addition, we offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates. Our product quality control indicators meet rigorous requirements for clinical use samples. It takes only a few weeks for us to produce 1 to 30 grams of purified monoclonal antibody from gene sequencing.


o Solutions

 Organoid Research Solutions
 Influenza Vaccine Solutions
 Multispecific Antibody Solutions
 Solutions for CAR-NK Therapy
 Solutions for In Vitro Efficacy Evaluation
 Solutions for CAR-T Therapy

o Featured Products

 GMP Grade Cytokines
 High Quality Cytokines
 Organoid Culture Cytokines
 Biotinylated Proteins
 Full Length Multipass Transmembrane Proteins
 Cell-based Activity Validated Proteins
 SEC-HPLC Verified Proteins
 Recombinant Allergens
 IGFBPs Proteins and Antibodies
 iPSC Cytokines
 More Hot Products

o Research Spotlights

 CAs: Promising Targets in Tumor Microenvironment
 MMPs: Regulators of Cancer Invasion and Metastasis

o ProVir® Viral Reagent Bank

 Influenza Vaccine Antigens
 Influenza HA Trimer Protein
 Immunodetection for Pan Influenza NP Antigens
 Pan Influenza A and B Antibodies
 SARS-CoV-2 Variants
 More 50+ Viruses

o Hot Research Topics

 Influenza Virus
 Virus Reagents
 Cytokines & Growth Factors
 Immune Checkpoints
 Targeted Therapy
 Immunotherapy
 Drug target
 Fc Receptors
 Biomarkers
 Enzymes & Kinase
 CD Antigens
 Receptors
 Signal Transduction
 Complement System

o Proteins

o Antibodies

 EliteRmab®
 Primary Antibodies
 Control Antibodies
 Loading Controls
 Phospho-Specific Antibodies
 Tag Antibodies
 Neutralizing Antibodies
 Virus Antibodies
 In Vitro Diagnostic Antibodies

o cDNA / Genes

 Lentiviral ORF Clones
 cDNA Clones in Cloning Vectors
 Expression-ready ORF Clones
 Control Vectors

o Transfection Reagents

o Serum-free Media

 HEK293 Media
 Insect Media
 CHO Media
 Hybridoma Media

o Kits

 ELISA Kits
 Cytokine ELISA Kits
 ELISA Matched Antibody Pairs
 SuperNuclease ELISA Kit

o Protein Modification

 Neuraminidases (NAs)
 Proteases
 SuperNuclease
 GMP-grade SuperNuclease

o qPCR Primers

o Cell Lysates

o Antibody Purification Reagents

 Protein A/G/L Resins
 Protein A/G/L
 Anti-DYKDDDDK Affinity Resin


o Center for Bioprocessing

o Quote for CRO Service

o Featured CRO Services
 Cell-Free Protein Expression Service
 Mammalian Transient Expression Services
 Recombinant Antibody Production Services
 Beacon® Single B Cell Screening Service
 Multi-pass Transmembrane Protein Development
 Hybridoma Development Services

o Protein Expression Services

 VLP-based Protein Expression Service
 Bacterial Protein Expression Service
 Transient Protein Expression Service
 Baculovirus Expression Service
 Stable Cell Line Development Services

o Technical Resources
 Recombinant Protein Resources
 Antibody Technical Resources

o Custom Antibody Services

 AI-Powered Affinity Maturation Service
 Recombinant Ab Production
 Cell-Free Protein Expression Service

 High-throughput Antibody Production

 Large-scale Antibody Production
 Chimeric Antibody Production
 Fab/scFv Antibody Production
 Bispecific Antibody Production
 Custom pAb Production Services
 Standard Rabbit pAb Service
 Custom Phospho-Specific Antibodies
 Anti-Idiotype Antibody Services
 Fast Antibody Production Services
 Antigen Production Service
 ELISA Kit Development
 Antibody Humanization Service
 Custom mAb Production Services
 Rabbit mAb Service
 Standard Mouse mAb Service
 Single B Cell Antibody Service
 Phospho-Specific Antibody Services
 Anti-Idiotype Antibody Services

o Biological Assay Services

 SPR/BLI Assay Services
 Assay Stable Cell Line Generation

Strengths of Sino Biological

Innovation permeates all aspects of Sino Biological’s enterprise, making it one of the largest mainstream suppliers of protein and antibody research tools in the world. Its one-stop shop integrates R&D, production and sales.

Advanced core technologies
Sino Biological has a suite of advanced core technologies. The company’s established technology platforms have full-level carrying capacity, with the ability to move research and development from the pilot test phase to full-scale production. The platforms can realize high-throughput and high-efficiency research and production of recombinant protein or antibody reagents.
Stringent quality control systems
Sino Biological follows stringent standards and quality control systems in developing and producing biological reagents.

• Company protocols assure the high quality of Sino Biological’s products by using advanced protein and antibody detection equipment;

• Providing powerful cell biological activity analysis;

• Employing perfect QA and QC quality assurance controls;
Basic physical and chemical assay, Enzymatic activity assay, Functional activity assay at the cellular level, Assay at molecular level, Virology assay, Immunological assay• All products are produced in house.

• Flexibility to Meet Industrial RequirementsLow Endotoxin Levels, High Monomer Purity (by SDS-PAGE & HPLC), Protein-Protein Interaction Analysis (BLI), Tag Removal Service, Buffer Screening and Stability Study, Glycosylation Analysis, Peptide Mapping

Qualifications and Honors