Description

Shepherdin (79-87) is amino acids 79 to 87 fragment of Shepherdin. Shepherdin is a peptidomimetic antagonist of the complex between Hsp90 and Survivin. Anticancer activity[1].—Cancer-programmed cell death–C41H64N12O12S—-[1]Plescia J, et al. Rational design of shepherdin, a novel anticancer agent. Cancer Cell. 2005 May;7(5):457-68.–861224-28-4–949.09—-CC(C)C[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC([C@H](C)NC([C@H](CS)NC(CNC([C@H](CO)NC([C@H](CO)NC([C@H](CC2=CNC=N2)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O–Cancer–H2O–HSP;Survivin–HSP90–Apoptosis;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease–Peptides