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RIPK1-IN-12-Get quote

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Description

RIPK1-IN-12 is a potent RIPK1 inhibitor. RIPK1-IN-12 inhibits necroptosis in both human and mouse cells, with EC50 values of 1.6 and 2.9 nM, respectively[1].—COVID-19-immunoregulation–C24H26N4O3S—-[1]Li Z, et al. Design, synthesis, and evaluation of potent RIPK1 inhibitors with in vivo anti-inflammatory activity. Eur J Med Chem. 2022, 228:114036.–2173556-92-6–450.55—-O=C(OC1CCCCC1)NC2=CC(C3=CC=C4N=C(NC(C5CC5)=O)SC4=C3)=CN=C2C–Inflammation/Immunology–10 mM in DMSO–Necroptosis;RIP kinase–RIPK1–Apoptosis–Peptides

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MEDCHEM EXPRESS