Description

Practolol-d7 is the deuterium labeled Practolol. Practolol is a potent and selective β1-adrenergic receptor antagonist. Practolol can be used for the research of cardiac arrhythmias[1][2][3].–Applications–Formula-C14H15D7N2O3-Citation–References-[1]Iakovidis D, et, al. In vitro activity of RO363, a beta1-adrenoceptor selective agonist. Br J Pharmacol. 1980 Apr;68(4):677-85.|[2]Adashi EY, et, al. Stimulation of beta 2-adrenergic responsiveness by follicle-stimulating hormone in rat granulosa cells in vitro and in vivo. Endocrinology. 1981 Jun;108(6):2170-8.|[3]Marshall RJ, et, al. Comparative effects of propranolol and practolol in the early stages of experimental canine myocardial infarction. Br J Pharmacol. 1976 Jun;57(2):295-303.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. -CASNumber-2714414-11-4-MolecularWeight-273.38-Compound Purity–SMILES-CC(NC1=CC=C(OCC(O)CNC([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C=C1)=O-Research_Area-Cardiovascular Disease-Solubility-10 mM in DMSO-Target-Adrenergic Receptor;Isotope-Labeled Compounds-Isoform–Pathway-GPCR/G Protein;Neuronal Signaling;Others-MCE Product type-Isotope-Labeled Compounds