Description
PDZ1 Domain inhibitor peptide, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)–Neuroscience-Neuromodulation–C38H61N9O11—-[1]Andrea Piserchio, et al. Targeting specific PDZ domains of PSD-95; structural basis for enhanced affinity and enzymatic stability of a cyclic peptide. Chem Biol. 2004 Apr;11(4):469-73.–1315378-73-4–819.94–98.10–O=C([C@H](CCCCN)NC([C@@H](N)CC1=CC=C(O)C=C1)=O)N[C@@H]2C(N[C@@](C(N[C@@H](CCC(NCCCC2)=O)C(N[C@@H](C)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)([H])[C@H](O)C)=O–Neurological Disease–H2O–iGluR—-Membrane Transporter/Ion Channel;Neuronal Signaling–Peptides
