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NH2-PEG8-acid-100 mg

100 mg

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Description

NH2-PEG8-acid is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. NH2-PEG8-acid also is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].-4°C (Powder, protect from light)-Applications-Cancer-programmed cell death-Formula-C19H39NO10-Citation–References-[1]Michael Nathaniel ALONSO, et al. Antibody adjuvant conjugates. WO2018009916A1.|[2]”An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. “-CASNumber-756526-04-2-MolecularWeight-441.51-Compound Purity-98.0-SMILES-O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCN-Research_Area-Cancer-Solubility-DMSO : 50 mg/mL (ultrasonic)-Target-ADC Linker;PROTAC Linkers-Isoform-Non-cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related

Brand

MEDCHEM EXPRESS