Description
NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. NH2-PEG2-C2-Boc is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].–20°C, 3 years; 4°C, 2 years (Powder)-Applications-Cancer-programmed cell death-Formula-C11H23NO4-Citation–References-[1]Han X, et al. Discovery of ARD-69 as a Highly Potent Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor (AR) for the Treatment of Prostate Cancer. J Med Chem. 2019 Jan 24;62(2):941-964.|[2]Joshua D. Thomas, et al. Pyrrolobenzodiazepine antibody conjugates. WO2019126691A1.-CASNumber-756525-95-8-MolecularWeight-233.30-Compound Purity-99.62-SMILES-NCCOCCOCCC(OC(C)(C)C)=O-Research_Area-Cancer-Solubility-DMSO : ≥ 100 mg/mL-Target-ADC Linker;PROTAC Linkers-Isoform-Alkyl/ether Linkers;Non-cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related
