N-CBZ-Phe-Arg-AMC-Get quote

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Description

N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a cathepsin substrate used in assessment activity of lysosomal cathepsin enzymes[1][2].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)—-C33H36N6O6—-[1]Xu P, et al. Ascorbic acid modulation of iron homeostasis and lysosomal function in trabecular meshwork cells. J Ocul Pharmacol Ther. 2014 Mar-Apr;30(2-3):246-53.|[2]Porter K,et al. Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. Autophagy. 2013 Apr;9(4):581-94.–65147-22-0–612.68–99.88–CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@@H](NC(OCC2=CC=CC=C2)=O)CC3=CC=CC=C3)=O)=O)C=C1O4)=CC4=O–Others–10 mM in DMSO–Cathepsin—-Metabolic Enzyme/Protease–Peptides

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MEDCHEM EXPRESS

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