Moexipril-d5-10mg
Description
Moexipril-d5 is the deuterium labeled Moexipril. Moexipril hydrochloride is a potent orally active non-sulfhydryl angiotensin converting enzyme(ACE) inhibitor, which is used for the treatment of hypertension and congestive heart failure[1][2].–Applications-Neuroscience-Neurodegeneration-Formula-C27H29D5N2O7-Citation–References-[1]Chrysant, S.G. and G.S. Chrysant, Pharmacological and clinical profile of moexipril: a concise review. J Clin Pharmacol, 2004. 44(8): p. 827-36.|[2]Edling, O., et al., Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril. J Pharmacol Exp Ther, 1995. 275(2): p. 854-63.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[4]Song, J.C. and C.M. White, Clinical pharmacokinetics and selective pharmacodynamics of new angiotensin converting enzyme inhibitors: an update. Clin Pharmacokinet, 2002. 41(3): p. 207-24.-CASNumber-1356929-49-1-MolecularWeight-503.60-Compound Purity–SMILES-C([C@@H](N[C@@H](CCC1=C(C(=C(C(=C1[2H])[2H])[2H])[2H])[2H])C(OCC)=O)C)(=O)N2CC=3C(C[C@H]2C(O)=O)=CC(OC)=C(OC)C3-Research_Area-Cardiovascular Disease-Solubility-10 mM in DMSO-Target-Angiotensin-converting Enzyme (ACE);Apoptosis;Isotope-Labeled Compounds-Isoform–Pathway-Apoptosis;Metabolic Enzyme/Protease;Others-MCE Product type-Isotope-Labeled Compounds