Methoxyfenozide-d9-Get quote

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Description

Methoxyfenozide-d9 is the deuterium labeled Methoxyfenozide[1]. Methoxyfenozide, a diacylhydrazine insecticide, selectively binds to lepidopteran ecdysone receptors (EcRs) over dipteran EcRs with Kd values of 0.5 and 124 nM, respectively. Methoxyfenozide is lethal to neonatal larvae of S. exigua, S. frugiperda, T. ni, O. nubilalis, L. pomonella, H. zea, and H. virescens (LC50s=0.35, 0.2, 0.11, 0.18, 0.21, 0.79, and 3.12 mg/L, respectively)[2].–Applications–Formula-C22H19D9N2O3-Citation–References-[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Trisyono, A., et al. Effect of the nonsteroidal ecdysone agonists, methoxyfenozide and tebufenozide, on the European corn borer (Lepidoptera: Pyralidae). J. Econ. Entomol. 90(6), 1486-1492 (1997).-CASNumber-2469014-53-5-MolecularWeight-377.52-Compound Purity–SMILES-O=C(C1=C(C(OC)=CC=C1)C)NN(C(C)(C)C)C(C2=C([2H])C(C([2H])([2H])[2H])=C([2H])C(C([2H])([2H])[2H])=C2[2H])=O-Research_Area-Others-Solubility-10 mM in DMSO-Target-Isotope-Labeled Compounds-Isoform–Pathway-Others-MCE Product type-Isotope-Labeled Compounds

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MEDCHEM EXPRESS

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