MC-Val-Cit-PAB-vinblastine-10 mg

Description
MC-Val-Cit-PAB-vinblastine is a agent-linker conjugate for ADC with potent antitumor activity by using vinblastine (an microtubule protein inhibitor), linked via the ADC linker MC-Val-Cit-PAB.-4°C (Powder, sealed storage, away from moisture and light)-Applications-Cancer-programmed cell death-Formula-C74H97N10O15-Citation–References-[1]Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.-CASNumber-2055896-92-7-MolecularWeight-1366.62-Compound Purity-90.17-SMILES-CC[C@@]12[C@@]3([H])[C@]4(CCN3CC=C2)[C@](N(C)C5=CC(OC)=C([C@@]6(C7=C(CC[N@@+]8(CC9=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCNC(C=CC=O)=O)=O)=O)=O)C=C9)C[C@@](C[C@](CC)(O)C8)([H])C6)C=CC=CC=CN7)C(OC)=O)C=C45)([H])[C@](C(OC)=O)(O)[C@@H]1OC(C)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-Drug-Linker Conjugates for ADC-Isoform-Traditional Cytotoxic Agents-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related