MC-Val-Cit-PAB-duocarmycin (chloride)-5 mg

5 mg

SKU: HY-128904-5 mg Category: Tags: ,

Description

MC-Val-Cit-PAB-duocarmycin chloride is a agent-linker conjugate for ADC with potent antitumor activity by using Duocarmycin (a DNA minor groove binding alkylating agent), linked via the ADC linker MC-Val-Cit-PAB.–20°C (Powder, protect from light, stored under nitrogen)-Applications-Cancer-programmed cell death-Formula-C54H65Cl2N9O9-Citation–References-[1]Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.-CASNumber-2055896-98-3-MolecularWeight-1055.05-Compound Purity-98.16-SMILES-ClC[C@H]1C2=C(C=C(O)C3=CC=CC=C23)N(C(C4=CC5=CC(OCC[N+](C)(C)CC6=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCCCN7C(C=CC7=O)=O)=O)=O)=O)C=C6)=CC=C5N4)=O)C1.[Cl-]-Research_Area-Cancer-Solubility-DMSO : 130 mg/mL (ultrasonic)-Target-Drug-Linker Conjugates for ADC-Isoform-Duocarmycins-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related

Brand

MEDCHEM EXPRESS

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