MC-Sq-Cit-PAB-Gefitinib-Get quote

Description
MC-Sq-Cit-PAB-Gefitinib is a agent-linker conjugate for ADC with potent antitumor activity by using Gefitinib (an EGFR tyrosine kinase inhibitor), linked via the ADC linker MC-Sq-Cit-PAB.–Applications-Cancer-Kinase/protease-Formula-C50H61ClFN10O9-Citation–References-[1]Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.|[2]FLYGARE, John A, et al. Quaternary amine compounds and antibody-drug conjugates thereof. WO2016090050A1.-CASNumber-1941168-63-3-MolecularWeight-1000.53-Compound Purity–SMILES-COC1=CC2=[N+](CC3=CC=C(NC([C@@H](NC(C4(C(NCCCCCN5C(C=CC5=O)=O)=O)CCC4)=O)CCCNC(N)=O)=O)C=C3)C=NC(NC6=CC=C(F)C(Cl)=C6)=C2C=C1OCCCN7CCOCC7-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-Drug-Linker Conjugates for ADC-Isoform-Traditional Cytotoxic Agents-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related