ALFAGEN, Your Long-Term Partner In Life-Science

JAK2/TYK2-IN-1-Get quote

Get quote

Add to Wishlist
Add to Wishlist

Description

JAK2/TYK2-IN-2 is a potent and selective TYK2 inhibitor with IC50 values of 9 and 157 nM for TYK2 and JAK2, respectively. JAK2/TYK2-IN-2 has anti-inflammatory activity[1].—COVID-19-immunoregulation–C19H13F4N7O2S—-[1]Zhang C, et al. Discovery of 3-(4-(2-((1H-Indol-5-yl) amino)-5-fluoropyrimidin-4-yl)-1H-pyrazol-1-yl) propanenitrile Derivatives as Selective TYK2 Inhibitors for the Treatment of Inflammatory Bowel Disease. J Med Chem. 2021; 64(4):1966-1988. –2613434-12-9–479.41—-N#CCCN1N=CC(C2=NC(NC3=CC4=C(N(S(=O)(C(F)(F)F)=O)C=C4)C=C3)=NC=C2F)=C1–Inflammation/Immunology–10 mM in DMSO–JAK–JAK2;Tyk2–Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt–Peptides

Brand

MEDCHEM EXPRESS