Description

IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate is an antagonist of interferon γ (IFN γ). IFN-γ Antagonist 1 inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells with an IC50 value of approximately 35 μM. IFN-γ Antagonist 1 has potential applications in immune regulation[1].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)—-C117H198N34O36S—-[1]Seelig GF, et al. Development of a receptor peptide antagonist to human gamma-interferon and characterization of its ligand-bound conformation using transferred nuclear Overhauser effect spectroscopy. J Biol Chem. 1995 Apr 21;270(16):9241-9.—-2689.10–99.87–O=C([C@H]1N(CCC1)C(CNC([C@H]([C@@H](C)CC)NC([C@H](CCCCN)NC(CNC([C@H](CC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CSCNC(C)=O)NC([C@@H](NC([C@@H](N)C)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)=O)=O)N3[C@@H](CCC3)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O–Inflammation/Immunology–H2O : 33.33 mg/mL (ultrasonic)–IFNAR—-Immunology/Inflammation–Peptides