Description
H-Glu-OtBu is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). H-Glu-OtBu is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2–20°C, 3 years; 4°C, 2 years (Powder)-Applications-Cancer-programmed cell death-Formula-C9H17NO4-Citation–References-[1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.|[2]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.-CASNumber-45120-30-7-MolecularWeight-203.24-Compound Purity-98.0-SMILES-N[C@@H](CCC(O)=O)C(OC(C)(C)C)=O-Research_Area-Cancer-Solubility-DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)-Target-ADC Linker;PROTAC Linkers-Isoform-Non-cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related
