Description
Guanylyl Imidodiphosphate (Guanosine 5′-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies[1][2][3].–Applications-Metabolism-protein/nucleotide metabolism-Formula-C10H17N6Na3O13P3-Citation–References-[1]Mitsunori Kawato, et al. Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway. J Biol Chem. 2008 Jan 4;283(1):166-174.|[2]J Goldberg, et al. Structural basis for activation of ARF GTPase: mechanisms of guanine nucleotide exchange and GTP-myristoyl switching. Cell. 1998 Oct 16;95(2):237-48.|[3]C Gaudin, et al. Overexpression of Gs alpha protein in the hearts of transgenic mice. J Clin Invest. 1995 Apr;95(4):1676-83.-CASNumber-148892-91-5-MolecularWeight-591.16-Compound Purity–SMILES-O[C@H]1[C@](O[C@@H]([C@H]1O)COP(OP(NP(O)(O)=O)(O)=O)(O)=O)([H])N2C3=C(C(N=C(N3)N)=O)N=C2.[Na].[Na].[Na]-Research_Area-Endocrinology-Solubility-10 mM in DMSO-Target-Adenylate Cyclase-Isoform–Pathway-GPCR/G Protein-MCE Product type-Biochemical Assay Reagents
