Description

Galanin (1-29)(rat, mouse) TFA is a non-selective galanin receptor agonist, with Kis of 0.98, 1.48 and 1.47 nM for GAL1, GAL2 and GAL3, respectively. Anticonvulsant effect[1][2].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)–Neuroscience-Neuromodulation–C141H211N43O41.xC2HF3O2—-[1]Wang S, et al. Cloning and expressional characterization of a novel galanin receptor. Identification of different pharmacophores within galanin for the three galanin receptor subtypes. J Biol Chem. 1997;272(51):31949-31952.|[2]Mazarati A, et al. Regulation of kindling epileptogenesis by hippocampal galanin type 1 and type 2 receptors: The effects of subtype-selective agonists and the role of G-protein-mediated signaling. J Pharmacol Exp Ther. 2006;318(2):700-708.—-3164.45 (free base)–99.67–OC(C(F)(F)F)=O.OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(NCC(N2[C@@H](CCC2)C(N[C@H](C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H](C(NCC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)[C@H](O)C)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CN=CN5)=O)=O)=O)=O)=O)CC6=CN=CN6)=O)=O)=O)=O)=O)NC(CNC([C@H](C)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@@H](NC(CN)=O)CC7=CNC8=CC=CC=C78)=O)=O)=O)=O)=O)=O)=O–Neurological Disease–10 mM in DMSO–Neuropeptide Y Receptor—-GPCR/G Protein;Neuronal Signaling–Peptides