Description

F1324 acetate is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6), with an IC50 of 1 nM. F1324 acetate exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI[1].—Cancer-programmed cell death–C83H121N21O20S.xC2H4O2—-[1]Sakamoto K, et al. Discovery of high-affinity BCL6-binding peptide and its structure-activity relationship. Biochem Biophys Res Commun. 2017 Jan 8;482(2):310-316.—-1765.04 (free acid)—-[Ac-LWYTDIRMSWRVP-OH (acetate)]–Cancer–10 mM in DMSO–Bcl-2 Family—-Apoptosis–Peptides