Description
Duocarmycin MA is an antibody agent conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. Duocarmycin MA can be used against multi-agent resistant cell lines.–Applications-Cancer-programmed cell death-Formula-C34H31ClN4O5-Citation–References-[1]Searcey M. Duocarmycins–natures prodrugs? Curr Pharm Des. 2002;8(15):1375-89.-CASNumber-1613286-57-9-MolecularWeight-611.09-Compound Purity–SMILES-O=C(OC(C)(C)C)NC1=CC=C(C(NC2=CC3=C(C=C2)C=C(C(N4C[C@@H](CCl)C5=C4C=C(O)C6=CC=CC=C56)=O)N3)=O)C=C1-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Cytotoxin;DNA Alkylator/Crosslinker-Isoform-Duocarmycins-Pathway-Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage-MCE Product type-ADC Related
