Description

DNase I (EC 3.1.21.1) is an enzyme that degrade DNA, it plays a key role in the cleavage of extracellular DNA is crucial for limiting the inflammatory response and maintaining homeostasis. Exogenous deoxyribonuclease shows beneficial effects in inflammatory diseases and cancer[1].–20°C-Applications-COVID-19-immunoregulation-Formula-N/A-Citation–References-[1]Lauková L, et al. Deoxyribonucleases and Their Applications in Biomedicine. Biomolecules. 2020 Jul 11;10(7):1036.|[2]Sugihara S, et al. Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice. Br J Cancer. 1993 Jan;67(1):66-70.-CASNumber-9003-98-9-MolecularWeight-N/A-Compound Purity–SMILES-[DNase I, Bovine pancreas]-Research_Area-Cancer; Inflammation/Immunology-Solubility-DMSO : 43.48 mg/mL (adjust pH to 3 with 1M HCl)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)-Target-Others-Isoform–Pathway-Others-MCE Product type-Enzyme