Description

DBCO-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.–20°C, 3 years (Powder)-Applications-Cancer-programmed cell death-Formula-C23H18N2O5-Citation–References-[1]Method for identifying potential drug target protein useful for development of antibody drug, and method for producing antibody directed against target protein. WO2018151301A1.-CASNumber-1353016-71-3-MolecularWeight-402.40-Compound Purity-99.53-SMILES-O=C(CCC(ON(C(CC1)=O)C1=O)=O)N(C(C=CC=C2)=C2C#C3)CC4=C3C=CC=C4-Research_Area-Cancer-Solubility-DMSO : 50 mg/mL (ultrasonic)-Target-ADC Linker-Isoform-Cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related