DBCO-NHCO-PEG4-NH-Boc-25 mg

25 mg

SKU: HY-126884-25 mg Category: Tags: ,

Description

DBCO-NHCO-PEG4-NH-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.–20°C, 3 years; 4°C, 2 years (Powder)-Applications-Cancer-programmed cell death-Formula-C34H45N3O8-Citation–References-[1]Kuzmin A, et al. Surface functionalization using catalyst-free azide-alkyne cycloaddition.-CASNumber-1255942-12-1-MolecularWeight-623.74-Compound Purity-99.19-SMILES-O=C(OC(C)(C)C)NCCOCCOCCOCCOCCC(NCCC(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)=O)=O-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker;PROTAC Linkers-Isoform-Alkyl/ether Linkers;Cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related

Brand

MEDCHEM EXPRESS

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