Description

Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1β converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K+ deprivation-induced apoptosis of cerebellar granule neurons[1].–Applications–Formula-C61H76N12O14S-Citation–References-[1]Schulz JB, et al. Potassium deprivation-induced apoptosis of cerebellar granule neurons: a sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species. J Neurosci. 1996 Aug 1;16(15):4696-706.-CASNumber-161877-70-9-MolecularWeight-1233.39-Compound Purity–SMILES-O=S(O)(C1=CC=CC2=C1C=CC=C2NCCNC([C@H](C(C)C)NC([C@H]3N(CCC3)C([C@H](C)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@@H](NC(C4=CC=C(C=C4)/N=N/C5=CC=C(C=C5)N(C)C)=O)CC6=CC=C(C=C6)O)=O)=O)=O)=O)=O)=O)=O)=O-Research_Area-Others-Solubility-10 mM in DMSO-Target-Fluorescent Dye-Isoform–Pathway-Others-MCE Product type-Dye Reagents