Description
Cyclosomatostatin TFA is a potent somatostatin (SST) receptor antagonist. Cyclosomatostatin TFA can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size and sphere-formation in colorectal cancer (CRC) cells[1].—Cancer-programmed cell death–C46H58F3N7O8—-[1]Shirin R Modarai, et al. Somatostatin signaling via SSTR1 contributes to the quiescence of colon cancer stem cells. BMC Cancer. 2016 Dec 7;16(1):941.—-893.99—-O=C(N[C@@](C(N[C@@]1([H])[C@@H](C)OCC2=CC=CC=C2)=O)([H])CCCCN)[C@H](NC([C@@H](NC(CCCCCCNC1=O)=O)CC3=CC=CC=C3)=O)CC4=CNC5=C4C=CC=C5.OC(C(F)(F)F)=O–Cancer–H2O–Somatostatin Receptor–SSTR1–GPCR/G Protein;Neuronal Signaling–Peptides