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bs-43036P-Recombinant human SIGLEC15 protein, C-His (HEK293)

bs-43036P-Recombinant human SIGLEC15 protein, C-His (HEK293)

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Description

conjugation-Unconjugated-source-Recombinant human SIGLEC15 protein, C-His (HEK293) protein is expressed in HEK293 with C-His. It contains the amino acid sequence of 20-263/328.-gene_id-284266-swiss_prot-Q6ZMC9-applications-ELISA-species-Others-background-Two families of mammalian lectin-like adhesion molecules, the selectins and the sialoadhesins, bind glycoconjugate ligands in a sialic acid-dependent manner. The sialic acid-binding immunoglobulin superfamily lectins, designated Siglecs or sialoadhesins, recognize sialylated ligands and play a key role in mediating sialic-acid dependent binding to cells. Siglec-15 (sialic acid binding Ig-like lectin 15), also known as CD33L3, is a 328 amino acid single-pass type I membrane protein that contains one Ig-like C2-type domain and one Ig-like V-type domain. Expressed in dendritic and macrophage cells, Sinlec-15 interacts with DAP10 and DAP12 and binds to sialylated glycoproteins. The gene encoding Siglec-15 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases.-storage_buffer-0.01M TBS(pH7.4)-storage_condition-The product should be stored at -70°C or -20°C.-expression_system-HEK293-tag-C-His-purity-> 95% as determined by SDS- PAGE-endotoxin-Not Tested

Brand

BIOSS-USA