Description
conjugation-Unconjugated-source-Recombinant mouse CD40L protein, N-His (HEK293) protein is expressed in HEK293 with N-His. It contains the amino acid sequence of 112-260/260.-gene_id-21947-swiss_prot-P27548-applications-ELISA-species-Others-background-CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.-storage_buffer-0.01M TBS(pH7.4)-storage_condition-The product should be stored at -70°C or -20°C.-expression_system-HEK293-tag-N-His-purity-> 95% as determined by SDS- PAGE-endotoxin-Not Tested
