Description
conjugation-Unconjugated-source-Recombinant SARS-CoV-2 Nucleocapsid protein , N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of Met1-Ala419.-gene_id-43740575-swiss_prot-P0DTC9-applications-ELISA, SDS-PAGE-species–background-Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.-storage_buffer-Aqueous buffered solution containing 0.01M PBS(pH7.4) with 0.03% Proclin300.-storage_condition-The product should be stored at -70°C or -20°C.-expression_system-E.coli-tag-N-His-purity-> 95% as determined by SDS- PAGE-endotoxin-Not Tested
