Description
conjugation-Unconjugated-source-Recombinant human P53 protein, C-His protein is expressed in E.coli with C-His. It contains the amino acid sequence of 1-393/393.-gene_id-7157-swiss_prot-P04637-applications-ELISA-species-Others-background-This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].-storage_buffer-0.01M TBS(pH7.4)-storage_condition-The product should be stored at -70°C or -20°C.-expression_system-E.coli-tag-C-His-purity-> 95% as determined by SDS- PAGE-endotoxin-Not Tested
