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Biotin-VAD-FMK-1 mg

1 mg

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Description

Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates.–20°C, 3 years; 4°C, 2 years (Powder)-Applications-Cancer-programmed cell death-Formula-C30H49FN6O8S-Citation–References-[1]Li J, et al. Nitric oxide suppresses apoptosis via interrupting caspase activation and mitochondrial dysfunction in cultured hepatocytes. J Biol Chem. 1999 Jun 11;274(24):17325-33.|[2]Samraj AK, et al. Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membranedepolarization. Mol Biol Cell. 2007 Jan;18(1):84-93.-CASNumber-1135688-15-1-MolecularWeight-672.81-Compound Purity-98.0-SMILES-COC(C[C@@H](C(CF)=O)NC([C@H](C)NC([C@H](C(C)C)NC(CCCCCNC(CCCC[C@@H]1SC[C@H](N2)[C@@H]1NC2=O)=O)=O)=O)=O)=O-Research_Area-Cancer-Solubility-DMSO : ≥ 27.3 mg/mL-Target-Caspase-Isoform-Caspase-Pathway-Apoptosis-MCE Product type-Biochemical Assay Reagents

Brand

MEDCHEM EXPRESS