Description
BAPTA is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2].–20°C, 3 years; 4°C, 2 years (Powder)-Applications–Formula-C22H24N2O10-Citation–References-[1]R Y Tsien, et al. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 1980 May 27;19(11):2396-404. |[2]Roger C Hardie, et al. Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N’,N’-tetraacetic acid (BAPTA) and di-bromo BAPTA. Cell Calcium. 2005 Dec;38(6):547-56. |[3]M B Collatz, et al. Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses. Cell Calcium-CASNumber-85233-19-8-MolecularWeight-476.43-Compound Purity-98.0-SMILES-O=C(O)CN(C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(O)=O)CC(O)=O)CC(O)=O-Research_Area-Others-Solubility-1M NaOH : 33.33 mg/mL (ultrasonic;adjust pH to 11 with NaOH)|DMSO : 15.62 mg/mL (ultrasonic;warming;heat to 60°C)-Target-Phospholipase-Isoform–Pathway-Metabolic Enzyme/Protease-MCE Product type-Biochemical Assay Reagents
