Description
BAPTA-AM is a well-known membrane permeable Ca2+ chelator. BAPTA-AM inhibits hERG channels, hKv1.3 and hKv1.5 channels in HEK 293 cells with IC50s of 1.3 μM, 1.45 μM and 1.23 μM, respectively[1].–20°C, 3 years; 4°C, 2 years (Powder)-Applications–Formula-C34H40N2O18-Citation–References-[1]Tang Q, et al. The membrane permeable calcium chelator BAPTA-AM directly blocks human ether a-go-go-related gene potassium channels stably expressed in HEK 293 cells. Biochem Pharmacol. 2007 Dec 3;74(11):1596-607.|[2]Wie MB, et al. BAPTA/AM, an intracellular calcium chelator, induces delayed necrosis by lipoxygenase-mediated free radicals in mouse cortical cultures. Prog Neuropsychopharmacol Biol Psychiatry. 2001 Nov;25(8):1641-59.-CASNumber-126150-97-8-MolecularWeight-764.68-Compound Purity-99.80-SMILES-O=C(OCOC(C)=O)CN(C(C=CC=C1)=C1OCCOC(C=CC=C2)=C2N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O-Research_Area-Cardiovascular Disease-Solubility-DMSO : 50 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic)-Target-Potassium Channel-Isoform–Pathway-Membrane Transporter/Ion Channel-MCE Product type-Biochemical Assay Reagents
