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Azetidin-3-ol (hydrochloride)-5 g

5 g

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Description

Azetidin-3-ol hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azetidin-3-ol hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthes PROTAC.-4°C (Powder, sealed storage, away from moisture)-Applications-Cancer-programmed cell death-Formula-C3H8ClNO-Citation–References-[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.-CASNumber-18621-18-6-MolecularWeight-109.55-Compound Purity-98.0-SMILES-OC1CNC1.Cl-Research_Area-Cancer-Solubility-DMSO : 25 mg/mL (ultrasonic)-Target-ADC Linker;PROTAC Linkers-Isoform-Non-cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related

Brand

MEDCHEM EXPRESS