Description

Aminooxy-PEG2-alcohol is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Aminooxy-PEG2-alcohol is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].–Applications-Cancer-programmed cell death-Formula-C4H11NO3-Citation–References-[1]Marek Kwiatkowski. Conjugates of biologically active molecules to functionalized polymers. WO2013186632A2.|[2]Murray BS, et al. Reactive thermoresponsive copolymer scaffolds. Chem Commun (Camb). 2010 Dec 7;46(45):8651-3.-CASNumber-185022-12-2-MolecularWeight-121.14-Compound Purity–SMILES-NOCCOCCO-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker;PROTAC Linkers-Isoform-Non-cleavable Linker;PEG Linkers-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related