Description

Adrenomedullin (porcine) is a peptide that regulates vasodilation. Adrenomedullin (porcine) induces endothelium-dependent relaxation in rat aorta with IC50 value of 2.4 nM. Adrenomedullin (porcine) induces endothelium-independent relaxation of porcine coronary arteries with an IC50 of 27.6 nM[1].—–C262H403N79O76S3—-[1]Yoshimoto R, et al. Effects of adrenomedullin and calcitonin gene-related peptide on contractions of the rat aorta and porcine coronary artery. Br J Pharmacol. 1998 Apr;123(8):1645-54.–912862-96-5–5971.68—-O=C([C@@H](N)CC1=CC=C(O)C=C1)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H]2[C@@H](C)O)=O)=O)CC3=CC=CC=C3)=O)CCCNC(N)=N)=O)CSSC[C@H](NC2=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N5[C@H](C(N[C@H](C(NCC(N[C@H](C(N)=O)CC6=CC=CC=C6)=O)=O)CCC(N)=O)=O)CCC5)=O)CO)=O)[C@H](CC)C)=O)CCCCN)=O)CO)=O)CCCNC(N)=N)=O)CCC4)=O)C)=O)C(C)C)=O)=O)CC(O)=O)=O)CCCCN)=O)CC(O)=O)=O)CCCCN)=O)CC(O)=O)=O)[C@@H](C)O)=O)CC7=CC=CC=C7)=O)CCC(N)=O)=O)CC8=CC=C(O)C=C8)=O)[C@H](CC)C)=O)CCC(N)=O)=O)CC9=CNC=N9)=O)C)=O)CC(C)C)=O)CCCCN)=O)CCC(N)=O)=O)C(C)C)=O)[C@@H](C)O)=O)=O)=O)CC=CC=CC=C)=O)CO)=O)CCCNC(N)=N)=O)CC(C)C)=O)=O)CCC(N)=O)=O)CC=CC=CC=C)=O)CC(N)=O)=O)CC(N)=O)=O)CCSC)=O)CO)=O)CCC(N)=O)=O)CCCNC(N)=N–Cardiovascular Disease–10 mM in DMSO–Others—-Others–Peptides