Description

Actinine-d9 chloride is the deuterium labeled Actinine chloride. Actinine chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat[1][2].-4°C (Powder, sealed storage, away from moisture)-Applications–Formula-C7H7D9ClNO2-Citation–References-[1]Koeth RA, et al. γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metab. 2014 Nov 4;20(5):799-812.|[2]Susumu Ogawa, et al. The Dynamics of Carnitine, γ-butyrobetaine and Trimethylamine N-oxide in Diabetics and the Effects of Changes in Renal Function. Ogawa et al., J Nephrol Ren Dis 2017, 1:2|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. -CASNumber-85806-17-3-MolecularWeight-190.72-Compound Purity-98.0-SMILES-[2H]C([N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])CCCC(O)=O)([2H])[2H].[Cl-]-Research_Area-Metabolic Disease; Cardiovascular Disease-Solubility-DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)-Target-Endogenous Metabolite-Isoform–Pathway-Metabolic Enzyme/Protease-MCE Product type-Isotope-Labeled Compounds