Description
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) is a high-affinity pentapeptide to bind to the src SH2 domain (IC50≈1 µM). Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA is an inhibitor for src SH3-SH2:phosphoprotein interactions[1].—Cancer-Kinase/protease–C34H47F3N5O19P—-[1]G J Pacofsky, et al. Potent dipeptide inhibitors of the pp60c-src SH2 domain. J Med Chem. 1998 May 21;41(11):1894-908.—-917.73—-O=C(O)CC[C@@H](C(O)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@H](CC1=CC=C(OP(O)(O)=O)C=C1)NC(C)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O–Cancer–H2O–Src—-Protein Tyrosine Kinase/RTK–Peptides
