Description

conjugation-Unconjugated-source-Recombinant human Fas Ligand Protein, N-His (HEK293) protein is expressed in HEK293 with N-His. It contains the amino acid sequence of 134-281/281.-gene_id-356-swiss_prot-P48023-applications-ELISA-species-Others-background-This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]-storage_buffer-Lyophilized from 0.22um filtered solution in PBS, 5mM DTT (pH=7.4). Normally 5 % trehalose is added as protectant before Lyophilization.-storage_condition-The product should be stored at -70°C or -20°C.-expression_system-HEK293-tag-N-His-purity-> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC-endotoxin-<1EU/ug by the LAL method