Description

conjugation-Unconjugated-source-Recombinant human TGFBR2 protein, C-hFc (HEK293) protein is expressed in HEK293 with C-hFc. It contains the amino acid sequence of 23-159/567.-gene_id-7048-swiss_prot-P37173-applications-ELISA-species-Others-background-This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.-storage_buffer-0.01M TBS(pH7.4)-storage_condition-The product should be stored at -70°C or -20°C.-expression_system-HEK293-tag-C-hFc-purity-> 90% as determined by SDS- PAGE-endotoxin-Not Tested