Description

Guanosine triphosphate-13C10,15N5 (tetraammonium) is the 13C and 15N labeled Guanosine triphosphate tetraammonium[1]. Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19[2].–Applications-Metabolism-protein/nucleotide metabolism-Formula-13C10H28N4 15N5O14P3-Citation–References-[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Abdo A Elfiky, et al. Anti-HCV, nucleotide inhibitors, repurposing against COVID-19. Life Sci. 2020 May 1;248:117477.-CASNumber–MolecularWeight-606.20-Compound Purity–SMILES-O[13C@H]1[13C@H]([13C@@H](O[13C@@H]1[13CH2]OP(OP(OP(O)(O)=O)(O)=O)(O)=O)[15N]2[13C]([15N]=[13C]([15NH]3)[15NH2])=[13C]([15N]=[13CH]2)[13C]3=O)O.N.N.N.N-Research_Area–Solubility-10 mM in DMSO-Target-DNA/RNA Synthesis;Endogenous Metabolite;Nucleoside Antimetabolite/Analog;SARS-CoV-Isoform–Pathway-Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease-MCE Product type-Isotope-Labeled Compounds