Description

Flurbiprofen-d3 is the deuterium labeled Flurbiprofen. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer[1][2][3].–20°C, 3 years; 4°C, 2 years (Powder)-Applications–Formula-C15H10D3FO2-Citation–References-[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Xiaobo Wang, et al. Flurbiprofen suppresses the inflammation, proliferation, invasion and migration of colorectal cancer cells via COX2. Oncol Lett. 2020 Nov; 20(5): 132.|[3]E M Glenn, et al. The pharmacology of 2-(2-fluoro-4-biphenylyl)propionic acid (flurbiprofen). A potent non-steroidal anti-inflammatory drug. Agents Actions. 1973 Nov;3(4):210-6.|[4]Hosoi, T., et al., Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress. EMBO Mol Med, 2014.-CASNumber-1185133-81-6-MolecularWeight-247.28-Compound Purity-99.94-SMILES-FC1=CC(C(C(O)=O)C([2H])([2H])[2H])=CC=C1C2=CC=CC=C2-Research_Area-Inflammation/Immunology; Cancer-Solubility-DMSO : 100 mg/mL (ultrasonic)-Target-Apoptosis;COX-Isoform–Pathway-Apoptosis;Immunology/Inflammation-MCE Product type-Isotope-Labeled Compounds