Description

Velaglucerase alfa is produced through gene activation technology and is identical to wild-type enzyme. Velaglucerase alfa targets accumulated glucocerebroside primarily within the lysosome of the macrophages in the affected organs and systems. Velaglucerase alfa is an enzyme replacement therapy (ERT) for type 1 Gaucher disease (GD)[1].–Applications-Metabolism-protein/nucleotide metabolism-Formula-N/A-Citation–References-[1]Morris JL. Velaglucerase alfa for the management of type 1 Gaucher disease. Clin Ther. 2012 Feb;34(2):259-71. -CASNumber-884604-91-5-MolecularWeight-N/A-Compound Purity–SMILES-[Velaglucerase alfa]-Research_Area-Metabolic Disease-Solubility-10 mM in DMSO-Target-Others-Isoform–Pathway-Others-MCE Product type-Enzyme