Description

D-Ala-Lys-AMCA hydrochloride is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA hydrochloride may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA hydrochloride can be used for characterizing PEPT1-specific substrates or inhibitors[1][2].–80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)-Applications-Cancer-programmed cell death-Formula-C21H29ClN4O6-Citation–References-[1]Gong Y, et al. Specific expression of proton-coupled oligopeptide transporter 1 in primary hepatocarcinoma-anovel strategy for tumor-targeted therapy. Oncol Lett. 2017 Oct;14(4):4158-4166.|[2]Groneberg DA, et al. Intestinal peptide transport: ex vivo uptake studies and localization of peptide carrier PEPT1. Am J Physiol Gastrointest Liver Physiol. 2001 Sep;281(3):G697-704. -CASNumber-2703746-41-0-MolecularWeight-468.93-Compound Purity-99.60-SMILES-NC1=CC=C(C(C)=C(CC(NCCCC[C@H](NC([C@@H](C)N)=O)C(O)=O)=O)C(O2)=O)C2=C1.[H]Cl-Research_Area-Cancer-Solubility-DMSO : 100 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)-Target-Fluorescent Dye-Isoform–Pathway-Others-MCE Product type-Dye Reagents