Description

Glycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local anesthetic that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease[1].–Applications-Cancer-Kinase/protease-Formula-C10H14N2O-Citation–References-[1]Strong JM, et al. Pharmacological activity, metabolism, and pharmacokinetics of glycinexylidide. Clin Pharmacol Ther. 1975 Feb;17(2):184-94.-CASNumber-18865-38-8-MolecularWeight-178.23-Compound Purity–SMILES-O=C(NC1=C(C)C=CC=C1C)CN-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-Drug Metabolite;ERK;MEK;NF-κB;Sodium Channel-Isoform–Pathway-MAPK/ERK Pathway;Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;NF-κB;Stem Cell/Wnt-MCE Product type-Biochemical Assay Reagents