Description

Guanosine 5′-diphosphate (GDP) sodium is a nucleoside diphosphate that activates adenosine 5′-triphosphate-sensitive K+ channel. Guanosine 5′-diphosphate sodium is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5′-diphosphate sodium can be used in the research of inflammation, such as anemia of inflammation (AI)[1][2].–Applications-COVID-19-immunoregulation-Formula-C10H14N5NaO11P2-Citation–References-[1]S Kajioka, et al. Guanosine diphosphate activates an adenosine 5′-triphosphate-sensitive K+ channel in the rabbit portal vein. J Physiol. 1991 Dec;444:397-418. |[2]Angmo S, et al. Identification of Guanosine 5′-diphosphate as Potential Iron Mobilizer: Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. Sci Rep. 2017 Jan 5;7:40097. -CASNumber-43139-22-6-MolecularWeight-465.18-Compound Purity–SMILES-O=P(OP([O-])(O)=O)(O)OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(N=C(N)NC3=O)=C3N=C2)O1.[Na+]-Research_Area-Inflammation/Immunology-Solubility-10 mM in DMSO-Target-Endogenous Metabolite;Potassium Channel-Isoform–Pathway-Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease-MCE Product type-Biochemical Assay Reagents