Description

BAPTA tetrapotassium is a selective chelator for calcium. BAPTA, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrapotassium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrapotassium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2][4].-4°C (Powder, sealed storage, away from moisture and light)-Applications–Formula-C22H20K4N2O10-Citation–References-[1]R Y Tsien, et al. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 1980 May 27;19(11):2396-404. |[2]Roger C Hardie, et al. Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N’,N’-tetraacetic acid (BAPTA) and di-bromo BAPTA. Cell Calcium. 2005 Dec;38(6):547-56. |[3]M B Collatz, et al. Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses. Cell Calcium-CASNumber-73630-08-7-MolecularWeight-628.79-Compound Purity-99.45-SMILES-O=C(O[K])CN(C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(O[K])=O)CC(O[K])=O)CC(O[K])=O-Research_Area-Others-Solubility-H2O : 125 mg/mL (ultrasonic)-Target-Phospholipase-Isoform–Pathway-Metabolic Enzyme/Protease-MCE Product type-Biochemical Assay Reagents