tans-4-Hydroxy-D-proline methyl ester (hydrochloride)-5 g

Description

tans-4-Hydroxy-D-proline methyl ester hydrochloride is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). tans-4-Hydroxy-D-proline methyl ester hydrochloride is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.-4°C (Powder, sealed storage, away from moisture)-Applications-Cancer-programmed cell death-Formula-C6H12ClNO3-Citation–References-[1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.|[2]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337.-CASNumber-481704-21-6-MolecularWeight-181.62-Compound Purity-98.0-SMILES-O=C(OC)[C@@H]1NC[C@H](C1)O.Cl-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker;PROTAC Linkers-Isoform-Non-cleavable Linker-Pathway-Antibody-drug Conjugate/ADC Related;PROTAC-MCE Product type-ADC Related