Description

MDTF free acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].–Applications-Cancer-programmed cell death-Formula-C16H11F4NO9S-Citation–References-[1]Dovgan I, et, al. 2-(Maleimidomethyl)-1,3-Dioxanes (MD): a Serum-Stable Self-hydrolysable Hydrophilic Alternative to Classical Maleimide Conjugation. Sci Rep. 2016 Aug 9;6:30835.-CASNumber-2102021-49-6-MolecularWeight-469.32-Compound Purity–SMILES-O=C([C@H]1CO[C@H](OC1)CN2C(C=CC2=O)=O)OC3=C(C(F)=C(C(F)=C3F)S(=O)(O)=O)F-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-ADC Linker-Isoform–Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related