Description

Mal-PEG8-Val-Ala-PAB-SB-743921 (Compound D7) is a Drug-Linker Conjugates for ADC. Mal-PEG8-Val-Ala-PAB-SB-743921 consists of KSP inhibitor SB-743921 (HY-14661) and a linker. Mal-PEG8-Val-Ala-PAB-SB-743921 can be used for synthesis of ADCs[1].–Applications–Formula-C73H96ClN7O19-Citation–References-[1]Li Y, et al. A novel antibody-KSP inhibitor conjugate improves KSP inhibitor efficacy in vitro and in vivo. Biomaterials. 2023 Jul 28;301:122258.-CASNumber–MolecularWeight-1411.03-Compound Purity–SMILES-O=C1C2=CC=C(Cl)C=C2OC(C(C(C)C)N(C(C3=CC=C(C)C=C3)=O)CCCNC(OCC4=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN5C(C=CC5=O)=O)=O)=O)=O)=O)C=C4)=O)=C1CC6=CC=CC=C6-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-Drug-Linker Conjugates for ADC-Isoform–Pathway-Antibody-drug Conjugate/ADC Related-MCE Product type-ADC Related