Description

Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine is an immune stimulator antibody conjugate (ISAC) comprising an anti-human epidermal growth factor receptor 2 (HER2) antibody, a STING agonist (ADU-S100) and a linker. Mal-VC-PAB-(N-Me-amide-C3)-ADU-S100 triethylamine can be uesd for cancer research (WO2018200812A1; example 5)[1].–Applications–Formula-C51H65N17O19P2S2.xC6H15N-Citation–References-[1]Thomas W. Dubensky Jr., et al. Antibody conjugates comprising sting agonist. WO2018200812A1.-CASNumber-2249935-19-9-MolecularWeight-N/A-Compound Purity–SMILES-O=C(CCCN(C)C(OCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCN(C2=O)C(C=C2)=O)=O)=O)=O)=O)O[C@H]3[C@H](N4C5=NC=NC(N)=C5N=C4)O[C@@](CO[P@]6(S)=O)([H])[C@@]3([H])O[P@](S)(OC[C@@]([C@H]7O)([H])O[C@@H](N8C9=NC=NC(N)=C9N=C8)[C@]7([H])O6)=O.CCN(CC)CC.[x]-Research_Area-Cancer-Solubility-10 mM in DMSO-Target-Drug-Linker Conjugates for ADC;EGFR;STING-Isoform-ErbB2/HER2-Pathway-Antibody-drug Conjugate/ADC Related;Immunology/Inflammation;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK-MCE Product type-ADC Related